Mesotherapy is a medical procedure that consists of multiple localised, superficial micro-injections of potent-active substances into the skin to effectively correct various manifestations of ageing skin.

It was developed by Dr Michel Pistor in the late 1950s and the term ‘mesotherapy’ derives from the word ‘meso’ which means ‘middle’ in Greek. It refers to the mesoderm, which is the embryonic tissue that forms the skin and connective tissue.

Mesotherapy Treatment FAQ's

Mesotherapy is used to:

  • Soften fine lines and wrinkles
  • Deeply hydrate skin
  • Provide potent antioxidant protection
  • Fade pigmentation and brighten uneven skin tone
  • Tighten loose skin through a mechanism of tissue regeneration and restructuring
  • Reduce cellulite
  • Treat hair loss, a condition commonly known as alopecia.

If we were to use one word to describe mesotherapy it would be ‘technique’. Precision in technique with highly effective cocktails and the correct frequency of treatments are the 3 key elements for a successful long lasting mesotherapy treatment.

The technique and depth of administration varies according to the area of application:

  • Combination of 3 different types of free-hand injections (superficial, intradermal and deep)
  • Use of an ultimate micro-needling pen for perfect synergy between technique and drug substances

The active substances found in the mesotherapy cocktails are vitamins, minerals, amino acids, nucleotides, antioxidants, plant extracts and high quality hyaluronic acid. At the Anti Wrinkle Clinic we only use products with proven efficacy, CE marking, pharmaceutical rigour and sterile packaging that preserve the quality and efficacy of the active ingredients. And so, we bring together two of the most well-known and highly effective mesotherapy brands:

  • mesohyal™ by mesoestetic with a line of 11 exclusive bespoke solutions
  • VISCODERM SKINKÒ and SKINKÒ E by IBSA, the company behind Profhilo, one of the most renowned and successful HA injectable treatments.

mesohyal™ by mesoestetic is the most extensive range of intradermal medical solutions with CE marking for safe and effective aesthetic treatments. The mesohyal™ line includes 11 unique products of high-quality hyaluronic acid of biotechnological origin combined with a full range of active substances to offer personalised solutions:

  1. mesohyal™ HYALURONIC a high concentration of HA for skin re-moisturising & rejuvenation
  2. mesohyal™ NCTC109 a cocktail of vitamins, a. acids, minerals & HA for intensive bio revitalisation
  3. mesohyal™ VITAMIN C a HA solution with ascorbic acid for antioxidant & brightening action
  4. mesohyal™ X-DNA a moisturising solution for protection of the cell membrane and tissue repair
  5. mesohyal™ ORGANIC SILICON a regeneration & restructuring solution
  6. mesohyal™ DMAE a blend of HA with dimethylaminoethanol to boost elasticity and firmness
  7. mesohyal™ OLIGOELEMENTS a revitalising solution combining numerous oligoelements & HA
  8. mesohyal™ BIOTIN a revitalising solution  with concentrated vitamins, mineral salts and HA
  9. mesohyal™ CARNITINE an anti-cellulite solution with L-Carnitine in a base of HA
  10. mesohyal™ ARTICHOKE a draining, detoxifying anti-cellulite solution with extract of artichoke
  11. mesohyal™ MELILOT an anti-cellulite solution combining extracts of mellow, troxerutin and HA

All active substances of the mesohyal™ range can be combined with one another which makes this product a unique and precise tool to address all manifestations of the ageing process of all skin types and for patients of all ages.

For optimum results, patients should have 5 sessions (1 session every 2 weeks). In addition, it is advisable to establish maintenance sessions every 3-6 months.


VISCODERM SKINKÒ and SKINKÒ E are antiageing and antioxidant complexes containing more than 50 dermofunctional elements including non cross-linked hyaluronic acid, 10 minerals, 20 amino acids and 9 vitamins B. SKINKÒ contains 2mg of hyaluronic acid in 5ml whereas SKINKÒ E contains 32mg of hyaluronic acid in 5ml.

The intended use of these solutions is to improve skin brightness, hydration, roughness and protect and repair damage caused by UV rays. It does this by creating an environment which maintains and improves cellular tropism of the epidermis and papillary dermis.

VISCODERM SKINKÒ and SKINKÒ E are injected in the superficial dermis of the face, neck, décolletage and hands. The result is visibly younger, healthier skin with increased skin tone, radiance and homogeneous colour.

This treatment is suitable for all skin types and for patients of all ages.

For optimum results, patients should have 4 treatments with 3 weeks intervals per cycle and 2 cycles per year.


Ageing is a multifactorial process; over time it affects different structures that lay beneath the skin. In younger age groups, mesotherapy is usually enough to address an individual concern, but in most cases, especially in the mature age groups, optimum results can only be achieved synergistically through a combination of treatments.

Patients often ask me for the “best” and the best can only be achieved when a series of treatments have been combined in a customised way. At the Anti Wrinkle Clinic we have been delivering bespoke treatments where mesotherapy is often used either on its own to address the signs of the ageing process or in combination with anti wrinkle injections, Profhilo, dermal fillers or microneedling to achieve natural-looking, long lasting results in an optimum way.

Treatment Costs

Mesotherapy - One-off Treatment - £380
Mesotherapy - Course of 3 Treatments - £900
Mesotherapy - Course of 5 Treatments - £1500

Booking & Enquires

What people say about us

Based on 152 reviews
I got married in October. I wanted to look gorgeous and flawless - every brides wish list. And Yiannis did just that for me. He provided a series of treatment which included anti wrinkles injections and Profilhio. He is so knowledgable and excellent at his job - he made me look so amazing at my wedding. I was so happy. His treatment made me glow and look so radiant. Thank you Yiannis for everything you did and contributing towards me looking the best I could ever have done for the best day of my life. I’m so grateful ♥️
Flora C.
Flora C.
I can’t speak more highly of Dr Yiannis. Both professionally and personally. He is such a kind, warm and welcoming doctor who takes the time to understand your skin concerns and then deliver the best treatment plan for maximum results. He takes the time to explain everything in detail as well as understanding the process and timings of the results. I’ve never had such an incredible service. He made me feel at ease the whole way and I trusted him fully. The results have been incredible! My skin looks and feels amazing. Thank you Yiannis. You are changing my relationship with my skin and I’m very thankful for you. See you soon!
I found Dr Yiannis through a Google search and thank you universe that I was connected with him.We went for Profilo and I’m over the moon with the results. Such a beautiful, natural look, my skin is so dewy and soft post treatment.It was the consultation that did it for me though. It was an absolute pleasure listening to Dr Yiannis talk so passionately about the treatments and his love for aesthetics.He was meticulous in his approach, cleaning my skin, measuring out the injection points - the treatment was painless and I experienced no bruising or swelling.I loved his energy and his holistic approach, I can’t wait to return and feel very fortunate to have being treated my him.Thank you Dr Yiannis.
I saw Dr Yiannis for cheek and lip enhancement, using dermal fillers, a few days ago. I am really impressed with the improvements, both to the contour of my face, and shape of my lips. Most importantly (to me), the results look completely natural. I just look fresher and younger which is exactly what I wanted.
Pablo Noceti T.
Pablo Noceti T.
When I met Dr Yiannis, I was so pleased to discover his holistic approach to aesthetics. He does not just promote his products( in my case I was interested in anti-aging boosters) but considers the whole patient. He spent time carefully explaining how the different treatments work but how these could be boosted through a healthier, active lifestyle , keeping hydrated, eating well, having a positive mindset. (All the things we know, but I really needed to hear them when I came to see the Doctor)!He is very passionate about this and is a walking advert! ( He practises what he preaches)! I was therefore naturally inspired and started on my own well being journey with small steps. At the same time we decided that Profhilo would be the best treatment for me. I am sure the booster on its own would have been great but over the two treatments and some of the lifestyle changes I incorporated as a result of Dr Yiannis' suggestions have meant that overall my 'small' changes have made a big impact and I feel, as a consequence my Profhilo treatments have yielded really great results. Dr Yiannis noticed these on my second follow up! I also feel my self confidence has really improved since the first time I went to the clinic. I really recommend the good doctor!Thank you Dr Yiannis, I will be returning for my top up treatment when they are due!
saadia Q.
saadia Q.
I went to see Dr Yiannis for Anti-Wrinkle Treatment and consultation to improve overall appearance of my face. Dr Yiannis took his time to explain options that he believed will help achieve what I was looking for. He is very professional and knowledgeable. He genuinely provided his recommendations and did not try to oversell other treatments/products he did not think I needed. I decided to have Profhilo treatment done, in addition to the Anti-Wrinke Treatment and after the first session, I’ve already seen great improvement and huge difference. My face no longer looks tired. My skin looks plump and bright. I have more even skin tone now. I just had the second session of Profhilo done yesterday and cannot wait to see more improvement on my skin. I will definitely come back for maintenance and other skin treatments I may need in the future. Many thanks Dr Yiannis.
Chris Y.
Chris Y.
I have to say Dr Yiannis exceeded all my expectations! I went to him with a lot of insecurity about my eye/eyebrow area and I was so amazed by his professionalism, patience and personalised approach to my concerns. I have had anti wrinkle treatments with him to prevent the formation of static lines in the eye area as well as Profhilo, which was honestly a game changer for my skin complexion, i loved it! If you are looking for someone with a lot of knowledge and expertise but also someone who is very compassionate and honest, he is the one to go to! I wouldn’t think I could find someone like him in London, the entire experience from consultation to treatment was superb (and he will dedicate as much time as you need to make sure you have the entire picture before proceeding with the treatment) Looking forward to seeing Dr Yiannis for future appointments :)
Marie N.
Marie N.
I had Profhilo treatment on my neck and from start to finish the service has been superb. Dr Yiannis is incredibly friendly and he clearly explained the procedure in detail providing me with the opportunity to ask lots of questions . I was quite nervous as it was my first time having profhilo but Dr Yiannis put me completely at ease.The procedure was almost painless and after 24 hours the small lumps ( which are normal following profhilo) had completely disappeared. 4 weeks later and the skin on my neck appears more hydrated and the neck lines are barely visible. I would definitely recommend!
I’m a very natural person and didn’t want any treatment that made me feel like I’m not myself. Prophilo with Dr Yiannis has been the best choice! I look like myself but fresh and youthful and natural! Highly recommend Dr Yiannis for helping you achieve a natural result! ❤️ Thank you Dr Yiannis!!
Eloise K.
Eloise K.
Very happy with the service and results from Dr Yiannis - he puts you at ease straight away and he is very knowledgable. He is also a kind and empathetic person. Highly recommended!
Kristina F.
Kristina F.
I wanted to hydrate my skin from the inside and chose Dr Yannis to carry out my first ever Profhilo treatment. Being a first timer, I was initially cautious, but he alleviated all my concerns by being a great listener as well as educating on the specifics of the treatment. I couldn't be happier with the end results! Thank you again.
Rebekka M.
Rebekka M.
Excellent experience with profhilo with a noticeable improvement to the texture of my complexion, giving a nice glow. Yiannis is always a pleasure to talk to, highly knowledgeable and informative. Highly recommended, both Yiannis and profhilo.
Rena K.
Rena K.

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